pentobarbital will lower the level or outcome of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Potent or reasonable CYP3A4 inducers may perhaps boost rate of diazepam elimination; therefore, efficacy of diazepam could possibly be decreased.
pentobarbital increases effects of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Warning/Monitor. Coadministration of ifosfamide with CYP2B6 inducers may possibly increase metabolism of ifosfamide to its metabolite. Check for greater effects/toxicities if mixed with CYP2B6 inducers.
pentobarbital will lessen the extent or outcome of almotriptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will minimize the level or outcome of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will decrease the level or impact of bazedoxifene/conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lessen the extent or effect of quetiapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
With therapeutic doses of TCAs, barbiturates raise metabolism and reduce blood concentrations of TCAs.
Contraindicated (1)pentobarbital will minimize the level or outcome of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital decreases levels of toremifene by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers boost level of toremifene metabolism, lowering the continuous-point out concentration in serum.
pentobarbital will minimize the extent or effect of estradiol vaginal by impacting hepatic/intestinal enzyme click here CYP3A4 metabolism. Use Warning/Watch.
Warning with use during surgeries or methods in little ones youthful than 3 yr or in pregnant Women of all ages for the duration of their 3rd trimester
pentobarbital will decrease the level or result of felodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the extent or outcome of ketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
Withdrawal signs manifest in infants born to moms who receive barbiturates through the past trimester of pregnancy